Testicular function among testicular cancer survivors treated with cisplatin-based chemotherapy

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Paternity and testicular function among testicular cancer survivors treated with two to four cycles of cisplatin-based chemotherapy.

BACKGROUND Preserved fertility is an important issue for testicular cancer (TC) survivors. OBJECTIVE Our aim was to examine any difference regarding paternity and testicular function following two, three, or four cycles of cisplatin-based chemotherapy for TC. DESIGN, SETTING, AND PARTICIPANTS A national multicentre follow-up survey assessing morbidity among survivors of unilateral TC diagno...

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Testicular function following chemotherapy.

Testicular dysfunction is a common long-term sequela of cytotoxic chemotherapy used in the treatment of many malignancies. The degree to which testicular function is affected is dose- and agent-dependent. The impact on germinal epithelial function of standard multi-agent regimens used in the treatment of lymphomas has been widely studied. Procarbazine-containing regimens result in azoospermia i...

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Vitamin D status among long-term survivors of testicular cancer

A correlation between disturbances in hormone levels and the onset of metabolic disorders has been reported in long-term survivors of testicular cancer (TC).We evaluated serum vitamin D levels and other biological parameters in a consecutive series of 61 long-term (≥3 years) unilateral TC survivors with a median a follow-up of 4 years and in a cohort of healthy males. Deficient vitamin D levels...

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Pulmonary function in long-term survivors of testicular cancer.

PURPOSE Long-term toxicity after cancer treatment has gained increasing clinical attention. We evaluated pulmonary function in long-term survivors of testicular cancer (TC). PATIENTS AND METHODS The pulmonary function of 1,049 TC survivors treated during 1980 to 1994 at three university hospitals in Norway was assessed by spirometry and a questionnaire (1998 to 2002). The patients were catego...

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ژورنال

عنوان ژورنال: Reproductive Medicine and Biology

سال: 2015

ISSN: 1445-5781

DOI: 10.1007/s12522-015-0232-6